4/6/2023 0 Comments Adrenaline is secreted byNorepinephrine causes vasoconstriction (a narrowing of the blood vessels) so is useful for maintaining blood pressure and increasing it in times of acute stress. This is norepinephrine acting as a neurotransmitter. Noradrenaline travels across the gap between two nerves where it binds to a receptor on the second nerve and stimulates that nerve to respond. Naturally occurring norepinephrine is mostly made inside nerve axons (the shaft of the nerve), stored inside vesicles (small fluid-filled sacs), then released when an action potential (an electrical impulse) travels down the nerve. Norepinephrine Vs epinephrine: Synthesis and Actions in the body It is mainly made in the adrenal medulla so acts more like a hormone, although small amounts are made in nerve fibers where it acts as a neurotransmitter. It is both a hormone and the most common neurotransmitter of the sympathetic nervous system. Norepinephrine is also known as noradrenaline. Norepinephrine is continuously released into circulation at low levels while epinephrine is only released during times of stress. Noradrenaline has a more specific action working mainly on alpha receptors to increase and maintain blood pressure whereas epinephrine has more wide-ranging effects. Although norepinephrine and epinephrine are structurally related, they have differing effects.
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